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While tirzepatide is not primarily eliminated through the kidneys, the gastrointestinal effects of the medication, including potential nausea, vomiting, and diarrhea, could lead to dehydration and electrolyte imbalances that may be particularly problematic in patients with compromised kidney function

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According to these observations, it emerges that the assessment of the association between the use of GLP1-RAs and the onset of thyroid tumors is complex and subject to varied interpretations

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